World’s Top-Rated 1 µL Spectrophotometer
DS-11 Series Spectrophotometers / Fluorometers combine 1µL UV-Vis, cuvette UV-Vis, and fluorescence into one instrument.
• Three Modes in One
• Powerful EasyApps™ Software
• SmartPath™ Technology
• Multi-Award Winning
• Flexible Export & Connectivity
• Maintenance-Free Design
DeNovix takes spectrophotometry to a whole new level of performance with the DS-11 Series. This easy-to-use, compact spectrophotometer delivers full spectrum UV-Vis analysis and fluorescence capability, making it ideal for rapid nucleic acid and protein quantification.
he DeNovix team developed a combination of opto-mechanical components and software algorithms that optimize results for every sample. Bridge Testing™ verification eliminates unreliable results that stem from broken sample columns or loading issues.
SmartPath algorithms ensure that the sample is only compressed, never stretched, to keep the column intact.
Multiple algorithms ensure confidence in results while also providing important information about possible sample anomalies.
Unmatched Sensitivity
The DS-11 Series uniquely integrates an optional 4-channel fluorometer. Fluorescence mode enables up to 1000x more sensitivity. DeNovix Fluorometers are compatible with a wide range of commonly used quantification assays.
Key Features
| 1. Sensitivity
Extend the lower detection limit for low concentration samples. Quantify down to 0.5 pg/µL dsDNA |
2. Specificity
Selectively quantify a sample in the presence of contaminants using DeNovix Fluorescence Quantification Assays. |
3. Total Sample QC
Combine Absorbance and Fluorescence measurements for specific quantification and reliable contamination detection. |
Ultimate Flexibility
Use standard quartz or disposable cuvettes for up to 10 mm pathlength absorbance measurements (190 – 840 nm).
Cuvette applications include nucleic acids, proteins, colorimetric assays, OD600 and custom standard curves. Systems include a cuvette block heater for Kinetics studies from 37 – 45°C.
The DS-11 Series combines the ease of use, wide dynamic range, and contamination detection of UV-Vis with the enhanced sensitivity and specificity of fluorescence quantification. This unmatched flexibility allows the DS-11 Series to excel in a wide range of applications.
| Nucleic Acid Quantification | · Measurement ranges
o 0.75 – 37,500 ng/µL dsDNA o 0.6 – 30,000 ng/µL RNA · Separate preconfigured apps for optimized workflow · Sample contaminant alerts · Preconfigured and user defined factors for ssDNA ensures appropriate concentration calculations · 260/280 and 260/230 ratios displayed · 11 Preconfigured dyes and fluorophores for Microarray · Option to add an unlimited number of new dyes for quick recall in Microarray |
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| Protein Quantification | · Measurement range
o 0.04 – 1,125 mg/mL BSA · Preconfigured and user defined protein types for A280 and Labeled Proteins · Preconfigured Peptide app for easy peptide analysis at A205/215 · Quick addition of new user defined protein types for improved workflow · Ultra short pathlength enables high absorbance capability: up to 750 mg/mL BSA · 11 Preconfigured dyes and fluorophores for Labeled Proteins · Option to add an unlimited number of new dyes for quick recall in Labeled Proteins · BCA, Bradford, Lowry and 660 nm colorimetric assays optimized for ease of use · Quick save and recall of standard curves available |
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| Fluorescence Quantification |
*Using DeNovix Fluorescence Quantification assays. For other kits please see manufacturer’s specifications. Custom Fluorescence Apps
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| UV-Vis and Custom Apps |
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| Kinetics and OD600 |
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| DS-11 FX+ | DS-11 FX | DS-11+ | DS-11 | DS-C | QFX | |
| 1 µL UV-Vis Samples | ✅ | ✅ | ✅ | ✅ | – | – |
| Cuvette Absorbance | ✅ | – | ✅ | – | ✅ | – |
| Fluorescence | ✅ | ✅ | Add On | Add On | Add On | ✅ |
| Detection Limit (dsDNA) | 0.0005 – 37,500 ng/µL |
0.0005 – 37,500 ng/µL |
0.75 – 37,500 ng/µL |
0.75 – 37,500 ng/µL |
0.04 – 75 ng/µL | 0.5 pg/µL – 4,000 ng/µL |
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dsDNA
RNA
ssDNA
Microarray
A280
Peptides
Labeled Proteins
Colorimetrics
Fluoro dsDNA
Fluoro RNA
Fluoro ssDNA
Fluoro Protein
Fluoro Custom Methods
Basic Fluorometer
UV-Vis
Formula Methods
Standard Curve Methods
Kinetics
OD 600