CleanNGS

The CleanNGS kit offers a highly efficient magnetic bead based clean-up system for the purification of both DNA and/or RNA for next-generation sequencing and sanger sequencing workflows. It can also be used for CRISPR-Cas9. CleanNGS provides maximum flexibility allowing for left, right or double-sided size selection by easily adjusting the sample to CleanNGS volume ratio(s).

Based on CleanNA’s proprietary chemistry CleanNGS removes, salts, primers, primer-dimers and dNTPs, while DNA and/or RNA fragments are selectively bound to the magnetic particles based on their size. Purified DNA and RNA is eluted of the magnetic particles using water or a low salt buffer and can be used directly for downstream applications. The protocol can be adapted to your current liquid handling workstation (e.g. Hamilton, Beckman, Agilent, Caliper, Perkin Elmer, Tecan and Eppendorf) utilizing your current protocol as well as being used manually.

Amplicons purified with CleanNGS system are ready to be used in the following applications:

 Next-Generation Sequencing

 PCR

 Genomic DNA clean up

 RNA clean up

 Fragment Analysis

 Microarrays

 Restriction enzyme clean up

 Cloning