High-performance automation designed to meet the workflow challenges of today’s life science lab.
Value-driven features aloe configuration of the ideal system for your application. Proudly designed and built in the U.S.A.
• Automated pipetting done smarter
• Complex pipetting made easy
• Large volumes at high throughput
The Lynx Liquid Handling Robot Series Platform (Workstation) is designed to meet the current application needs of today’s life science companies. Through the implementation of Volume Verified Pipetting (VVP) technology in the 96/24 VVP & f8 VVP pipetting tools, we now directly measure liquid entering and leaving the tip volumetrically, creating a final validation report that methods are accomplished as programmed. These VVP pipetting tools take the guesswork out of pre-validated methods running water, reagents with dye or multiple dispenses over a balance to ‘average out’ how individual liquids may be handled. Now, validated reports are the standard, with actual volumes recorded at each liquid aspirate/dispense activity. Reports are stored in the same folder as all the other standard sample tracking information, such as sample bar codes, tip and plate bar codes, reagent lot number, and more. Combine VVP technology with your choice of multiple deck sizes, Standard Volume (SV) syringe-based 96 & 384 pipetting tools, microplate gripper tools and vision scanning tools to configure just about any combination for a liquid handling robotic system equipped to accomplish your application.
Aspiration and dispense of the liquid sample is driven by the precise control of vacuum and positive pressure. A volumetric liquid transfer is accomplished in each channel by the coupling of a solenoid valve to a silicon chip based MEMS flow sensor in a closed loop real time environment, where the actual flow rate of a liquid is monitored. This allows liquids with different physical properties to flow into/exit the tip while automatically accommodating for temperature and viscosity differences.
VVP technology also provides Liquid Level Detection (LLD) for each channel utilizing clear tips in both the 96 & 8 channel pipetting tools. The system creates an outward flow of air and monitors this airflow until a solid meniscus is detected. The Residual Volume within the well is then calculated based on the vertical height of the tip at the contact point with the solid meniscus and the well volume parameters.
Short sample or Air-In-Sample diagnostics is established by the monitoring of all channels with millisecond sampling analyzing the flow rate of the liquid into each tip. Any disruption of the samples flow rate by air entering a channel traps Short Sample Error. The end user may predetermine how to handle this Short Sample Error, including an on-the-fly retry of the aspiration, dispense all samples
back to the source well, or transfer the volume and report the actual ‘short’ volume transferred.
The Short Sample diagnostics technology is employed to verify that no air is aspirated as the Tip Tracking function is utilized. If the sample is aspirated faster than the tip tracks down, the Tracking Error is trapped for the individual channel(s).
Volume Verified Pipetting technology from Dynamic Devices validates liquid transfers, with full liquid handling diagnostics and volumetric sample tracking. Combinations with our standard spreadable 8 tip and 96 / 384 channel syringe based pipetting tools ,linear motion technology, microplate gripper tools, machine vision error handling and bar code scanning, the most powerful liquid handling robot can be configured to fit just about any laboratory automation application.
Why Choose the Lynx LM Series Liquid Handling Robotic Platform? Absolute Positioning with Linear Magnetic Motors & Encoders Linear motors and encoders provide superior positional accuracy, precision and repeatability to the mechanical rotation-to-translation mechanisms such as racks & pinions or belts & pulleys commonly found in laboratory liquid handling instruments. In addition, linear motors and encoders provide increased speeds reduced maintenance and on the pipetting tool positional encoding.
Supreme Flexibility with an Unrestricted Worktable
Each Lynx worktable position includes an SBS complainant microplate footprint that provides organizational flexibility with any combination of plates, tips or disposables. The superior strength in the instrument chassis and vertical drive allows the Lynx to load 96 or 384 tips from any of the possible 66 worktable locations. This flexibility, combined with a complete disposable tip line each available in an SBS free standing tip box, provides a flexible yet highly functional worktable.
Advanced Motion Controls
The Lynx offers the latest linear drives and advanced motion controls commanding highly precise positioning and repeatability with virtually no maintenance. The per motion axis modular architecture includes a solo high flex cable with a single connector containing both the power and communications, providing simplicity and reliability.
Open Design For Flexible Integration
Microplate gripper options give the Lynx flexible integration capabilities from simple pipette head grippers to 6 axis SCARA robots that can reach off deck to incorporate other peripherals. The open chassis design allows integration from all 4 sides, as well as horizontal conveyor options and vertical incorporation through the worktable.
Low Maintenance Solid Mandrel Tip Loading
The Solid Mandrel (SM) tip adapters for the loading of disposable pipette tips has abolished the need for maintaining high maintenance components like rubber O-rings and tip seals. The SM tip loading eliminates the need for a 3 or 6-month preventive maintenance service by excluding the highest maintenance component on the robot.
Simplified Programming with Method Manager 4.0
Method Manager 4.0 provides an intuitive and simplified way to program your methods, import files, export your pipetting data, and manage pipetting diagnostics and error handling routines.
Award-winning Volume Verified Pipetting (VVP) technology represents the very latest in air-based 8, 24 & 96 multi-channel pipetting.
Highly sensitive in-line flow sensors integrated into each and every channel translates to unique pipetting competencies
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| Independent Volumes on All Channels
· Superior flexibility for 96 & 24-channel automated liquid handling · Expands pipetting workflow efficiency by several-fold over traditional tools · Perform plate normalizations, serial dilutions & other common routines in record time |
Direct Volumetric Measurement of Each & Every Transfer
· Ultimate pipetting confidence with real-time volume verification · Removes the guesswork from automated liquid handling once-and-for-all · Any liquid, at any volume…with zero liquid class development |
Live Pipetting Diagnostics & Error Recovery
· New levels of process security with continuous QC monitoring of all channels · More robust workflows with advanced user-defined recovery for ‘on-the-fly’ corrections · Final validation data report captures all pipetting data |
| VVP air-based pipetting tools perform all aspirate and dispense functions via precise control of vacuum and positive pressure, respectively.
A silicon chip-based MEMS micro-sensor assembly incorporated into each liquid channel measures the pressure differential across a known constriction. Volumetric flow rate is a linear function of this pressure differential, allowing for instantaneous calculation of the actual volume of liquid entering or leaving each tip. By monitoring and adjusting to volumetric flow in real-time, all pipetting processes can be controlled and finely tuned for any liquid, automatically accommodating for temperature and viscosity differences.
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Liquid Level Detection (LLD) with VVP
Independent-channel LLD on all liquid types is performed via controlled micro-releases of air from the distal end of the tip and subsequent monitoring of pressure changes associated with meniscus (or bubble/foam) interference. A residual volume based on the confirmed meniscus height and labware definition is calculated. Any pipetting discrepancies experienced are addressed via several user-defined error recovery options.
Air-based VVP technology accomplishes robust LLD without the need for more expensive carbon-impregnated (capacitance-based LLD) disposable tips. For the best pipetting results, be sure to use D2-brand ‘performance-certified’ clear disposable tips.
Pipetting Diagnostics with VVP
VVP performs continuous millisecond analysis of flow rates for each liquid channel. A disruption in the expected average flow rate, produced either by air entering the channel (i.e. ‘short or no sample’) or a blockage (i.e. clot/clog) triggers an alert.
Diagnosed pipetting errors are addressed automatically ‘on-the-fly’ via user-defined error recovery options.
Independent control of each channel affords the freedom to isolate and disable only the offending channel(s), allowing the method to continue without interruption.
Upon method completion, a final Error Report file is generated.
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| Advanced Clot/Clog Detection & Correction
Characteristics of the sample matrix are used to set specific flow rate measurement thresholds, allowing optimal detection and recovery from blockages such as clots or clogs. Upon detection, affected channel(s) are disabled and remaining tips finish aspirating. Upon completion, the VVP head is raised, affected tip(s) cleared and an ‘intra-well re-aspiration’ is performed. |
Short Sample/No Sample Detection & Correction
Flow rate changes caused by introduction of air into the sample column during aspiration are used to diagnose a ‘short sample’ or ‘no sample’ specimen. Recovery options include skip the sample, re-aspirate, sample blow-back, or dispense and report the actual volume transferred |
Featuring next-gen integrated flow sensor technology. Fast and flexible, perfectly suited for liquid handling in single microliter to milliliter volumes.
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| 96VVP Pipetting Tool
96 channel (8×12) head; fixed 9mm spacing · 96 independent volumes with LLD & Pipetting Dx on each channel · Wide dynamic range: 1.5 μL – 1,250 μL/channel · 96 volume transfers simultaneously monitored, verified and recorded in real-time The only 96-channel head on the market with 96 independent volumes, allowing for new levels of flexibility and efficiency. Yields unsurpassed speed in combinatorial pipetting routines, normalization, serial dilutions, pooling, hit picking and complex plate layouts. |
24VVP Pipetting Tool
24 channel (4×6) head; fixed 18mm spacing · 24 independent volumes with LLD & Pipetting Dx on each channel · Wide Dynamic Range: 50 μL – 5,000 μL/channel* · 24 verified volume transfers simultaneously monitored, verified and recorded in real-time *using D2 performance-certified DDX-24 5mL disposable tips The only 24-channel head on the market with 5mL/channel capacity. Ideal for applications such as liquid biopsy sample distribution and large volume DNA mag-bead based extraction. 24 independent volumes offers flexibility for more complex pipetting routines. |
Fixed 8VVP Pipetting Tool
8 channel (1×8) tool; fixed 9mm spacing · 8 independent volumes · Wide Dynamic Range: 0.5 μL – 1,250 μL/channel · 8 verified volume transfers simultaneously monitored, verified and recorded in real-time The Lynx’s entry-level VVP tool (f8) transfers 8 independent volumes of liquid with verified volume reporting and full pipetting diagnostics. For samples within microplate format you can now validate your transfers with our fixed-8 tip VVP Pipetting Tool. By eliminating the independent spreading and Z axis capabilities, multiple axis control is reduced, providing a highly economical yet functional VVP pipetting tool. |
f8iz Pipetting Tool
8 channel (1×8) tool; independent z-axis · 8 independent volumes · Wide Dynamic Range: 0.5 μL – 1,250 μL/channel · Independent z-axis motion per individual tip · Independent access to variable spaced tubes and individual wells possible · Verified and recorded in real-time Our newest VVP pipetting tool has the capability of independent z-axis motion per individual tip with a fixed y-axis. With independent Z, individual access to variable spaced tubes and individual wells is possible. The f8iz VVP uses the same clear tips as the other VVP tools; has independent Liquid Level Detection (LLD), linear motors, a volume range from 1 to 1250uL as well as full VVP pipetting diagnostics for each channel. |
Traditional syringe-drive air-based pipetting; uniform volume across all channels. An economical solution for many liquid-handling applications such as plate stamping. Single, row and column tip pick up. For 24, 96, 384 & 1536-well plate-based liquid handling routines.
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| 24ST Pipetting Tool
24 uniform volume channels Our 24 ST Pipetting Tool allows 24 5mL disposable tips to be used for uniform volume transfers. Fast pipetting of all your large volume samples. Now accomplish applications like In-Parallel Mag Bead Extraction. |
96ST Pipetting Tool
96 uniform volume channels; 8×12 array; fixed 9mm spacing Our 96 ST Pipetting Tool allows the transfer of wells, rows, columns or entire 96 well plates across 96, 384 or even 1536 well plates. In this ST syringe based design, identical volumes are transferred in every channel. The dual disposable tip mandrel design provides options for low and high volume configurations. With replaceable CORE insert pipetting blocks, the 96 ST syringe pipetting tool is the most economical for high throughput liquid handling. |
384ST Pipetting Tool
384 uniform volume channels; 16×24 array; fixed 4.5mm spacing With the high loading force required to load 384 simultaneous tips, the Lynx is specifically engineered to load these tips from any worktable position. No specific loading areas or specialty tip loading tools required. Simply place the 384 tip box(es) in any microplate position and run your method with the versatility you expect from your Lynx LM Series Workstation. |
| Pipetting Tool | DDX96 60 μL
non-filtered |
DDX96 340 μL
non-filtered |
DDX96 1250 μL
non-filtered |
LXB96 200 μL
non-filtered |
LXB96 300 μL
non-filter |
LXB96 1250 μL
non-filtered |
| High Volume
96ST Head |
1.0 μL – 60 μL
(35 μL filtered) |
1.0 μL – 340 μL
(230 μL filtered) |
1.0 μL – 1000 μL
(1000ul filtered) |
1.0 μL – 200 μL
(150 μL filtered) |
1.0 μL – 300 μL
(250 μL filtered) |
1.0 μL – 1000 μL
(950 μL filtered) |
*lower volumes may be achieved under optimal conditions
| Pipetting Tool | DDX384 30 μL
non-filtered |
DDX384 70 μL
non-filter |
DDX384 (96 format) 70 μL
non-filtered |
LXB384 30 μL
non-filtered |
LXB384 70 μL
non-filtered |
| Low Volume
(384) 96ST Head |
X | X | 1.0 μL – 70 μL | X | X |
| 384ST Head | 1.0 μL – 30 μL
(15 μL filtered) |
1.0 μL – 70 μL
(50 μL filtered) |
X | 1.0 μL – 30 μL
(15 μL filtered) |
1.0 μL – 70 μL
(50 μL filtered) |
*lower volumes may be achieved under optimal conditions
Positional Accuracy and Reproducibility
Linear drive motors coupled with x/y axes positional encoders provides unparalleled accuracy and zero drift over time. < 0.1 mm positional resolution allows robust pipetting to high-density 1536-well plates.
Lynx incorporates a series of enabling technologies for robust performance and reduced maintenance.
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| Sturdy Chassis
· Rigid aluminum frame provides structural integrity to withstand rigors of extended operation · Stiffness ensures consistent x/y axes positional performance over time · Load full rack, rows or columns of tips from any location on the deck without the need for special tip-loading modules |
Solid Mandrel Design
· Stainless steel adapters for reproducible tip pickup and ejection · Zero wear parts (i.e. no O-rings or motors) for low maintenance operation · Single design compatible with all Lynx disposable clear tips |
Linear Motion Technology
· High-speed high precision linear motors coupled with positional encoders · Unparalleled x/y axes positional accuracy and zero drift over time · Pipetting/gripping arms know location at all times, even upon a crash · Re-start methods without re-initialization · Zero wear parts for maintenance-free operation |
Dynamic Loading & Storage Integration
We’re excited to introduce to you the NEWEST member of the Dynamic Devices product line Qdex! With the need for speed and ultimate flexibility, the NEW Qdex will solve your workflow bottlenecks holding up to 60 trays at a time. As displayed at SLAS 2020, Qdex is available for continuous operation with dynamic loading giving you uncompromising performance.
Virtual Deck | Faster Access | Random Access | Batch Processing | Continuous Loading | Multi-User Availability | SBS & Custom Labware | 4x the capacity
No more waiting to load or unload plates or trays
Normalize 270 plates in less than 4 hours
Exchange a tray of 9 plates in 30 seconds
18 virtual deck positions available
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| Seamless Integration with Lynx Workstation | Dynamic Loading/Unloading of Trays | Holds up to 60 Trays at a Time |
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| Head Gripper Tool cost-effective solution for on-deck labware transport; fingers configured onto 96 or 384 head arms; plate stacking/unstacking, lidding/de-lidding plates, move mag and vac separation devices, discard empty tip boxes and more |
‘iPaw’ Internal Gripper Tool flexible solution for on and off-deck labware transport; separate frame mounted arm ideal for hand-offs to readers, washers and other peripheral integrated devices; can ‘cross-over’ pipetting arms for increased flexibility and provide pipetting arms with increased access to on-deck positions |
External Gripper on Rail
for more complex integration projects that require plate transport of over longer distances to access larger peripherals, industrial 6-axis robot on 1-3 meter linear rail; provides full access to locations under deck, behind or to the sides of the system |
| Scanning
1D & 2D Scanning |
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| Instrument Control Software
Simplified Instrument Control |
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| Lynx Certified Disposable Tips
Clear Tips Standard Boxes |
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• Genomics
• Proteomics
• CellOmics
• Drug Discovery
• Applied Science
• Microarray
Lynx Platform Decks Sizes
Sizes & Capacities
Flexible, space-efficient decks to fit your ideal throughput and walk-away time; 5 models to choose from:
| Platform Deck | Length | Width | Height | Deck Positions (#’s) |
| LM1800 | 75“ | 36“ | 40“ | 60-66 |
| LM1200 | 52“ | 36“ | 40“ | 42 |
| LM900 | 40“ | 36“ | 40“ | 30 |
| LM700 | 28“ | 26“ | 26“ | 12 |
| LM730i | 24“ | 24“ | 30“ | 18 |
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