Why does centrifugation during an assay make my automation more complex?

A centrifuge needs to be in balance to operate properly. This is one of the first remarks made when an operator works with a centrifuge for the first time. There are numerous examples of accidents with centrifuges because of imbalanced loading. Luckily, modern technology allows for a tolerance in balance. This makes operating a centrifuge a lot easier for an operator.

Most automated centrifuges have two buckets to load plates. But not many automated systems are equipped with a weighing station. So, when working with plates with varying volumes in it, balancing out the centrifuge becomes a problematic step. Especially since a plate handler needs to have the same access point over and over again and moving a millimeter might already cause it to crash. The HiG centrifuges have a really high imbalance tolerance of up to 100 grams, without sacrificing into the speed (up to 5.000 g) eliminating the need for weighing a plate in most assays.

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