The genome of a species is not static. While there is a strong influence of the genotype on the phenotype, not all of the gene functions and expressions are due to changes in the DNA sequence alone. Many processes have been identified in which there is interaction with proteins or where post-synthetically changes to the DNA sequence are observed. The role of RNA and especially non-coding RNA (ncRNA) is a major controlling element in many epigenetic processes.
There are many methods to quantify DNA methylation. Among them are PCR, real-time PCR and high resolution melt curve assays. GC biotech offers the Bioline Epigenetics products to enable the research in these areas.
Our portfolio of products for Epigenetics includes:
Meridian Bioline Reagents
Meridian Bioscience is a fully integrated life science company that develops, manufactures, markets and distributes a broad range of innovative diagnostic products.
We are dedicated to developing and delivering better solutions that give answers with speed, accuracy and simplicity that are redefining the possibilities of life from discovery to diagnosis. Our molecular reagents are used by biologists and other research scientists to perform test-assays and research in many fields from medical, biotechnology and marine biology to food and agriculture technology as well as forensic and environmental sciences, where life scientists have come to depend upon the outstanding quality and reliability of our reagents.
We have developed and manufactured a portfolio of more than 300 reagents and kits, many of them proprietary, for molecular biology, cell analysis and nucleic acid and protein separation and purification. Meridian is an ISO 13485 certified company and one of the world’s few manufacturers of ultra-pure dNTPs, as well as a variety of enzymes and biochemicals. . Find out more…